Impact of COVID-19 Confinement on Quality of Life of Patients with Age-Related Macular Degeneration: A Two-Wave Panel Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36983394/
Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries. Intravitreal injections of antiangiogenic agents (anti-VEGF) can stop vision loss in the neovascular form of the disease...
Conclusion: Patients perceived a worsening in HRQoL after confinement. However, patients enjoyed good social support that improved in the after-COVID survey.
Bacillary Layer Detachment in Neovascular Age-Related Macular Degeneration: Case Series - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36979967/
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Conclusions: A bacillary layer detachment was detected in patients with neovascular age-related macular degeneration. This multimodal imaging finding is not commonly described in the literature for this disease.
Elevated number and density of macrophage-like cell as a novel inflammation biomarker in diabetic macular edema - Scientific Reports
Source : https://www.nature.com/articles/s41598-023-32455-1
To quantitatively analyze the number and density of macrophage-like cells (MLCs) at the vitreoretinal interface at macular region in diabetic retinopathy (DR) with and without diabetic macular edema (DME). This...
Conclusion: In summary, the number and density of MLCs at macular region were significantly higher with larger and fuller morphology in DR patients with DME than those without DME. PDR eyes had fewer MLCs than NPDR eyes for DR eyes without DME.
Adenosine Receptors Expression in Human Retina and Choroid with Age-related Macular Degeneration | Journal of Ophthalmic and Vision Research (JOVR)
Source : https://knepublishing.com/index.php/JOVR/article/view/12725
Purpose: Adenosine signaling modulates ocular inflammatory processes, and its antagonism mitigates neovascularization in both newborns and preclinical models of ocular neovascularization including age-related macular degeneration (AMD). The adenosine receptor expression...
Conclusion: The ocular presence of adenosine receptors is consistent with their proposed role in modulation of inflammation in both the retina and choroid, and their potential targeting for AMD treatment.
Age-Related Macular Degeneration and Its Association With Neurodegenerative Disorders
Age-related macular degeneration (AMD) is a highly prevalent macular condition that primarily affects the older population. It is the primary cause of blindness amongst the elderly population. It is an...
Conclusions/Relevance: Amyloid-β is an aberrant protein that accumulates within the brains of Alzheimer's patients and appears as plaques on magnetic resonance imaging (MRI). These plaques are a pathognomonic sign of Alzheimer's disease. Similar to this, amyloid-β deposits are reported to build up beneath the retina of AMD...