Retina Health Connect
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3yr
Efficacy and safety of curcumin in diabetic retinopathy: A protocol for systematic review and meta-analysis

Efficacy and safety of curcumin in diabetic retinopathy: A protocol for systematic review and meta-analysis

Source : https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0282866

Background Diabetic retinopathy (DR) is one of the most common complications of diabetes and has become a major global cause of blindness. Curcumin, an extract of Curcuma longa (turmeric), is...

Conclusion: This study will be the first meta-analysis to comprehensively assess the efficacy and safety of curcumin in the treatment of DR and will provide helpful evidence for the clinical management of this disease.
 

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3yr
Choroidal neovascularization removal with photo-mediated ultrasound therapy - PubMed

Choroidal neovascularization removal with photo-mediated ultrasound therapy - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37029733/

This study introduces PUT for the first time for the treatment of CNV. The results demonstrated good efficacy and safety of PUT to treat CNV in a clinically-relevant rabbit model....

Conclusions: This study introduces PUT for the first time for the treatment of CNV. The results demonstrated good efficacy and safety of PUT to treat CNV in a clinically-relevant rabbit model. With a single session of treatment, PUT can safely reduce the leakage of CNV for at least 1 month after treatment.
 

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3yr
Optical Coherence Tomography Angiography for Detecting Nonexudative Macular Neovascularization in Age-Related Macular Degeneration - PubMed

Optical Coherence Tomography Angiography for Detecting Nonexudative Macular Neovascularization in Age-Related Macular Degeneration - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37008398/

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Conclusions: OCTA is similarly effective as ICGA at detecting nonexudative MNV patterns.

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Dr. Michael Klufas

3yr
The advent of anti-VEGF biosimilars

Anti-VEGF therapies effectively treat retinal disease. By blocking VEGF signaling, they target vascular permeability, angiogenesis, and inflammatory responses. The advent of anti-VEGF therapies has improved patient outcomes in neovascular age-related macular degeneration (nAMD), macular edema after retinal vein occlusion (RVO), myopic choroidal neovascularization (mCNV), and diabetic macular edema (DME). However, reference products are expensive for both patients and healthcare systems.

Biosimilars help decrease the price of these important ophthalmic agents thereby increasing access to more patients. Financial savings from biosimilars not only increase patient access but may also help improve adherence and health outcomes.

What is your clinical experience with anti-VEGF biosimilars? What considerations do you make when prescribing these agents?

  • 3yr
    I do not see the clinical benefits that biosimilars offer to the current armamentarium of options available.
  • 3yr
    I am excited to learn more about biosimilars, but I would say at this point the jury is still out. I am optimistic about advances in this field and Show More

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3yr
Clinical implications of choroidal vascular brightness using ultra-widefield indocyanine green angiography in polypoidal choroidal vasculopathy - PubMed

Clinical implications of choroidal vascular brightness using ultra-widefield indocyanine green angiography in polypoidal choroidal vasculopathy - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37076505/

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Conclusions/Relevance: The UWF ICGA results showed an increase in CVB at the inferior quadrants and posterior pole, suggesting venous outflow congestion in PCV eyes. CVB might provide more substantial information on the phenotype than other choroidal vascular features.